Pancreatic cancer originates in the pancreas, an essential organ for digestion and blood sugar regulation. It is one of the deadliest cancers, with a five-year survival rate of less than 11%. This grim statistic is largely due to its silent progression and late detection. Symptoms, such as jaundice, back pain, and unintended weight loss, often appear only in advanced stages.

Who Is Most Affected?
Pancreatic cancer is more prevalent among individuals over 60. African Americans face a higher incidence rate compared to other racial groups in the U.S., influenced by a combination of genetic, socioeconomic, and lifestyle factors. People with diabetes, chronic pancreatitis, or a family history of pancreatic cancer are also at increased risk.

The Role of Genetic Testing and Family History
Genetic testing is crucial for identifying hereditary risks. Mutations in genes such as BRCA1, BRCA2, and PALB2 significantly increase the likelihood of pancreatic cancer. Families with histories of hereditary breast and ovarian cancer syndrome or Lynch syndrome should consider genetic counseling to explore preventive measures and early detection options.

Resources for Support and Education

• Pancreatic Cancer Action Network (PanCAN): Provides a wealth of information on risk factors, treatments, and ongoing research.
• Hirshberg Foundation for Pancreatic Cancer Research: Focuses on early detection initiatives and education.
• National Comprehensive Cancer Network (NCCN): Offers clinical practice guidelines for patients and healthcare providers.

The Need for Research and Innovation
Pancreatic cancer research has lagged behind other types of cancer, making advocacy for increased funding a priority. Promising advancements in immunotherapy and precision medicine offer hope, but more extensive research is needed to improve survival rates and quality of life for patients.